100 Random DND Potion Effects

Here’s a list of 100 random potion effects you can use in your fantasy tabletop RPG campaign.

1) You feel an overwhelming urge to sing, but the only song you can remember is the song of your god. You are, however, unable to sing it in your normal voice. Instead you sing in the voice of an elderly lady, in the style of a Norwegian troll. The effect is strangely haunting and beautiful, and everyone within hearing distance is entranced.

2) As you drink this potion, your body feels lighter and airier. You feel like you could literally fly away. And so you do. You take to the sky, soaring over the rooftops of the city. The sun is shining and the birds are singing. It’s a beautiful day. You cannot stop singing for 1d10 hours.

3) The potion takes effect almost immediately. You feel a burning sensation in your chest, and then a searing pain as your lungs fill with fire. You try to scream, but no sound comes out. You feel your body start to twitch and convulse. Then, just as quickly as it began, the pain subsides. You take a deep breath and feel oddly invigorated. Your lungs feel stronger than ever before, and you can breathe in deeply without any difficulty. You are also resistant to fire for 1d6 hours.

4) This pink liquid potion causes you to grow an extra set of arms that have the same strength and dexterity as your original arms. They are, however, covered in soft, downy feathers.

5) As you drink the potion, you feel a warm, tingling sensation all over your body. Suddenly, you feel like you can do anything. You feel strong, brave, and fearless. You feel like you can take on the world. The effect lasts for 1d6 hours. It’s a confidence booster and has no real magical effect.

6) This potion causes your skin to change color. It turns a deep, inky black, and your eyes turn a bright, luminous green. You feel powerful and dangerous, like a predator. The effect lasts for 1d6 hours.

7) As you drink the potion, you feel a sense of euphoria wash over you. You feel happy and content, like there’s nothing you can’t do. The effect lasts for 1d6 hours.

8) This potion turns your hair into a luxurious, shiny waterfall of gold permanently. Also, it won’t stop growing and cannot be cut.

9) The potion makes your voice change. It becomes much deeper and throatier, and you have a sudden urge to speak in alliteration. The effect lasts for 2d6+2 hours.

10) This potion causes your skin to become rough and scaly, like a snake’s. You feel strong and powerful, and you have a sudden urge to hiss and strike out at anyone who crosses your path. You are better protected. The effect lasts for 3d6 hours.

11) The potion makes your eyes change color. They become a deep, shimmering blue, and you have a sudden urge to stare into people’s souls. Strangers may become alarmed if you’re around. The effect lasts for 1d6 hours.

12) The potion makes your teeth grow into sharp, jagged fangs. You feel like a wild animal, and you have a sudden urge to hunt and kill. The effect lasts for 1d6 days.

13) The potion causes your body to become covered in thick, black fur. You feel strong and powerful, like a wild beast. The effect lasts for 1d6 days.

14) The potion causes you to become incredibly bloated. Your stomach swells up like a balloon, and you find it difficult to move. However, you feel incredibly content and happy, like you’re finally full after a long journey. The effect lasts for 1d6 days.

15) This potion makes you shrink in size until you are one inch tall. You will be this size for 2d10 minutes but won’t know how long it will last.

16) As you drink the potion, you feel a sense of warmth and well-being spreading through your body. You feel sleepy and content, like you could just curl up and take a nap. The effect lasts for 1d6 hours.

17) The potion makes your skin turn a deep, blood red. You feel hot and feverish, and you have a sudden urge to attack and kill anything that moves. You also get a bonus to hit during attack. The effect lasts for 1d6 hours.

18) The potion makes your eyes turn a milky white. You can’t see anything at all, but you can feel the presence of other beings around you. They’re cold and dangerous, and you can smell their blood in the air. The See Ghost effect lasts for 1d6 hours.

19) The licorice flavored potion causes you to become incredibly strong and fast. You feel like you could take on any opponent and win. The effect lasts for 1d6 hours.

20) A yellow-green potion imbues you with the strength of ten men (+3 strength for 2d20 hours).

21) Contained in a crystal bottle tinged pink, this potion will heal all wounds and restore all hit points, and you immediately vomit up 3d6x10 gp worth of treasure.

22) After drinking this potion you feel as light as a feather and can jump incredible heights and distances. Your movement speed is also doubled for the next 1d10 hours.

23) A black potion which smells of death and decay. When ingested you feel a coldness spreading through your body, a sense of emptiness. For the next 1d6 hours you will be immune to all damage, but cannot attack or be attacked. You are also completely immobile.

24) A cloudy white potion with a sweet vanilla scent. Drinking it will make you feel drowsy and content, like all your worries have been washed away. The effect lasts for 1d6 hours.

25) A bubbling, green potion that smells like sulfur and decay. When ingested you feel a burning sensation in your gut, and then an intense thirst. For the next 1d6 hours you will take double damage from all sources, but will be able to drink any amount of water without penalty. The potion was created by Zan the Wizard in order to win a water-drinking contest.

26) A deep, dark purple potion with a bitter licorice aftertaste. Drinking it will make you feel powerful and confident, like you could take on the world. It’s a false sense of bravado. The effect lasts for 1d6 hours.

27) A bright, sunny yellow potion that smells like lemons. Drinking it will make you feel energetic and happy. You gain +2 wisdom for 2d10 days. After the effects wear off, you permanently lose one point of wisdom.

28) A dark, murky, liquid that glows green when exposed to light. Drinking it will make you feel calm and centered, and filled with negative energy. The effect lasts for 1d4 hours. After the effects wear off, you gain 100 xp.

29) A dark, purple potion that smells like berries and tastes like berries, too. Drinking it will make you feel giddy and uplifted. It will make you immune to fear for 2d6 minutes.

30) A green liquid that doesn’t smell like much of anything, but tastes like boiled vegetables. Drinking it will give you the uncanny ability to move silently for 1d4 hours.

31) A bright, clear potion that smells like roses and tastes like strawberries. Drinking it will make you feel energetic and beautiful. You will get a +1 bonus to charisma, dexterity and wisdom for 2d12 hours. After effects wears off, you gain 100 xp, but also suffer a -1 penalty to charisma, dexterity and wisdom for 2d10 days.

32) A brown liquid that smells like fermented fruit and tastes like peach. Drinking it will make you feel strong and powerful. You will get a +1 bonus to strength and constitution for 1d12 hours. After effects wears off, you will gain 100 xp, but also suffer a -1 penalty to strength and constitution for 1d10 days.

33) A deep, red potion that smells strongly like wine and tastes of berries. Drinking it will make you feel strong and empowered. You will get a +1 bonus to strength, constitution and charisma for 2d10 days. After effects wears off, you gain 100 xp, but also suffer a -1 penalty to strength, constitution and charisma for 2d12 hours.

34) A bright, clear potion that is tinted yellow from the herbs used to make it. Drinking it will give you an ample amount of belly laughs for 1d4 hours. Your companions may not take kindly to this.

35) A murky green potion that smells like mint and tastes like asparagus. Drinking it will make you feel alert and on top of the world. It will give you +1 bonus to intellect for 1d12 hours.

36) A light blue potion that smells like the sea and tastes like olives. Drinking it will make you feel calm, relaxed, and ready to take on the world! It will give you +1 bonus to perception, intelligence, wisdom and dexterity for 1d12 hours.

37) A light, bubbling liquid that smells like wet fish and tastes like lobster bisque. Drinking it will make you feel energetic and positive! It will give you +1 bonus to dexterity, intelligence and perception for 1d12 hours.

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38) This bright blue potion will cause you to care less about how others see you, and more about how you see yourself. For 1d4 hours, you get +2 wisdom, but -1 charisma.

39) This orange potion smells strongly of pumpkin spice, and tastes like cinnamon. It will make you feel warm, safe and loved. You get +1 dexterity, perception, intelligence and wisdom to 2d12 hours, but suffer -1 dexterity, perception, intelligence and wisdom to the same amount on the other side.

40) This red potion smells strongly of peaches, and tastes like strawberries. It will make you feel energized, but also reckless and aggressive. You get +1 strength, dexterity and constitution for 1d12 hours.

41) This red potion smells like burnt peaches, and tastes like burnt bacon. It will give you +2 to combat rolls for 12 hours.

42) This slimy, red potion smells bittersweet, and tastes like dark chocolate. It will make you feel energetic, and a little giddy. You will get a +2 bonus to dexterity and intellect for 1d12 hours.

43) This slimy, blue potion smells like peaches and cream, and tastes like blueberries. It will make you feel happy and positive, but also a bit tired. You get a +1 bonus to wisdom and intellect for 1d12 hours.

44) This green, bubbling potion smells like peach, and tastes like sour cream. Drinking it will make you feel wiry and energetic, but also a bit sad. You get +1 dexterity and wisdom for 1d12 hours.

45) This bright blue potion smells like chocolate, and tastes like coffee. Drinking it will make you feel alert, awake and confident. You will also heal 2d10 damage.

46) A bright, bubbling potion that smells like apples and tastes like grapes. Drinking it will make you feel energetic and confident. You will get +1 strength and constitution for 1d12 hours.

47) A dark, murky potion that smells like raspberries and tastes like blackberries. Drinking it will make you feel warm, content and full. You will also get 2 points of natural healing.

48) A clear, bubbling brew that smells like warmed metal and tastes like butter. It will give you super fast reflexes. You gain +2 dexterity and +2 to initiative rolls for 1d4 hours.

8) A clear, bubbling brew that smells like warmed metal and tastes like butter. It will give you super fast reflexes. You gain +2 dexterity and +2 to initiative rolls for 1d4 hours. #DND #TTRPG #RPG #fantasy

49) A murky green potion that smells like rotten eggs. It tastes worse. Drinking it will make you feel healthy, but not very smart. You gain 2 hit points per level of your character, and a -1 penalty to wisdom and intellect for 1d4 hours.

50) A clear, bubbling brew that smells like coffee and tastes like blueberries. Drinking it will make you feel alert, and a little giddy. It will also grant you a +1 bonus to wisdom and intelligence for 1d12 hours.

51) This violet potion smells like smoke and tastes like tobacco. Drinking it will make you feel confident, but also uncomfortable in your own skin. You get a +2 bonus to dexterity, constitution and charisma for 1d12 hours, but suffer a -1 penalty to dexterity, constitution and charisma for 1d12 hours after the effect wears off.

52) A bright green potion that smells of waterfalls and tastes like honeydew. Drinking it will make you feel energetic and fast. You get +1 to dexterity, constitution and perception for 1d12 hours.

53) A blue potion that smells of bread and tastes like sour milk. Drinking it will make you feel happy and relaxed. You get a +1 bonus to intellect and perception for 1d12 hours.

54) A yellow potion that smells strongly of peaches and tastes like olives. Drinking it will make you feel lucky…or is it unlucky? You get +2 to all combat rolls except damage rolls for 1d12 hours.

55) A blue potion that smells like cinnamon and tastes like pumpkin pie. Drinking it will make you feel warm, safe and loved. You get a +1 bonus to intelligence, wisdom and dexterity for 1d12 hours.

56) A smoky red potion that smells like tobacco, and tastes like licorice. Drinking it will give you the uncanny ability to move quietly for 1d4 hours.

57) This light, murky potion smells strongly of cinnamon and tastes of maple syrup. Drinking it will give you the power to magically smell danger before it’s too late! For 1d4 hours you will gain +1 perception when rolling initiative and +1 initiative when rolling perception, but the effect wears off after the first encounter with danger.

58) This bubbling, green potion smells slightly of rotten eggs, but tastes of corn on the cob! Drinking it will make you feel giddy and crazy-like! You will get +200% on all damage rolls, tripling the damage.

59) This brownish-orange potion smells of milk, and tastes like chicken. Drinking it will make your skin as tough as leather – but only for 1d12 minutes!

60) This deep cobalt potion smells like chocolate and tastes of corn on the cob. Drinking it will make you feel tired and relaxed, like you’ve just woken up from a long nap. You start with a +2 bonus to all rolls for 1d4 hours.

61) A pale blue potion that smells strongly of mint and tastes of lemon. Drinking it will make you feel happy! You gain +1 to all stats for 1d4 hours.

Fantasy Potion Effects
Fantasy Potion Effects

62) A murky purple potion that smells of blackberries and tastes like grapes. Drinking it will temporarily cause all animal life forms (excepting rats) in 30ft to become friendly toward you for 1d4 hours.

63) A golden potion that’s so dark it appears black. It smells of cloves and tastes of strong ginger beer. Drinking it will fill you with a sense of foreboding and doom! For 1d12 hours you gain -2 to hit, but +2 to damage.

64) This dark green potion smells like mint and tastes of cilantro. Drinking it will temporarily grant out of this world vision! For 1d4 hours, you will be able to see as if it was twilight even in the brightest daylight. In addition, you gain +1 to your initiative rolls and perception rolls.

65) This shifty, iridescent potion smells of mushrooms, and tastes like gingerbread. Drinking it will give you the power to breath underwater for 1d8 hours or until you hit land again. You also gain +1 to your swimming skill during this time.

66) A jade-colored potion that smells of vanilla extract and tastes like honeyed apples. Drinking it will make you look younger and more vibrant for 1d12 hours! During this time, you gain +1 to charisma and all charm based skills, but also -1 to diplomacy, intimidate, persuasion and perception based rolls.

67) A misty-blue potion that smells strongly of mint and tastes of honey. Drinking it will make your body feel light as a feather! For 1d12 hours your maneuverability is doubled.

68) This forest green potion fizzles slightly and smells of lavender and lemon. Drinking it will make your skin feel cool and tingly! You gain +2 to all dexterity rolls for 1d12 hours!

69) A wispy yellow potion that makes your nose itch and eyes water. It smells like papaya, and tastes of chocolate. Drinking it will make you feel happy, peppy and energized! You gain +1 to all stats for 1d6 hours.

70) This dark violet potion that smells of chocolate and tastes like butterscotch gives incredible insight into your actions! For 1d12 hours you gain +10 perception on all saving throws and perception based rolls.

71) This silvery-blue potion that smells of olives and tastes of almond candy has a copper aftertaste. Drinking it will make you feel fearless and invulnerable! You gain +2 to dexterity and constitution for 1d12 hours.

72) This deep, blood red potion that smells strongly of grapes and tastes like oranges makes you feel fierce and strong like a wild beast! For 1d12 hours you gain +3 strength and a +2 bonus to all combat rolls, but a -2 penalty to dexterity, intelligence and perception based rolls.

73) This shimmering, iridescent potion that smells of vanilla and tastes like raspberries glows with a soft blue light. Drinking it will make you feel like you’re walking on clouds! For 1d12 hours, you gain +1 to dexterity and a +1 bonus to all combat rolls.

74) This lime-green potion that smells of popcorn and tastes like peppermint makes you feel focused and alert! For 1d6 hours you gain +1 to intelligence and perception.

75) This fiery orange potion smells of chocolate and tastes of blueberries. Drinking it will make your mind race, filling it with possibilities! For 1d4 hours you gain +2 to intelligence and wisdom.

76) A silvery-blue potion that smells like vanilla extract and tastes like honeyed apples. Drinking it will give you the uncanny ability to power through only a few hours of sleep per night! For 1d6 months, you won’t need more than 4 hours of sleep.

77) This murky, reddish-purple potion that smells of blackberries and tastes like grapes makes you feel stronger and tougher! For 1d12 hours, you gain +3 grit and +3 damage reduction, but -1 to your dexterity and intelligence stats.

78) A deep red potion that smells strongly of goldenrod and tastes like rye bread gives you the ability to dodge like the wind! For 1d4 hours all dodge checks are made with a +4 bonus.

79) This pale red potion smells of black pepper and tastes like apple cider. Drinking it will make you feel like you’re moving in slow motion! For 1d4 hours, all combat movement is increased by 50%, but your hit rolls are decreased by -2.

80) This dark pink potion smells of vanilla extract and tastes faintly of strawberries. Drinking it will make your wounds heal three times faster! For 1d6 hours, when you spend a healing surge, roll a d6: on a 5 or 6, your surge value increases by an additional +3 healing.

81) A pyrite-colored potion that smells of gingerbread cookies and tastes like roast beef makes your skin tougher! For 1d12 hours your hide gains a +1 natural armor rating.

82) A bubbling blue potion that smells strongly of pumpkin and tastes like cotton candy grants the ability to move with grace and agility. For 1d12 rounds you gain a +1 to initiative and Dexterity.

83) A tea-colored potion that smells of cinnamon and tastes like cornbread grants the user the ability to slow their heart and breathing. For 1d12 rounds you gain a +2 to Constitution and a +1 saving throws against poisons.

84) A red potion that smells faintly of cinnamon and tastes like rye bread causes you to become slightly hallucinogenic. For 1d12 rounds you gain a +2 to Wisdom and Intelligence, but suffer a -2 penalty to Charisma.

85) A golden-brown potion that smells slightly of steak and tastes of highland mead causes your body to become slightly grimy. For 1d12 hours you gain a +1 natural armor rating, but also suffer a +1 penalty to Charisma.

86) A murky white potion with a bubbly texture and an odd taste of gingerbread cookies causes your body to tingle with magical potential. For 1d12 hours your spellcasting ability is increased by 1d6 points of damage with each spell.

87) A murky purple potion that smells of strawberries and tastes like prune juice makes your muscles stronger. For 1d12 hours your Strength score is increased by 1d6 points.

88) A black potion made of bile and blood that smells like onions and tastes of brandy grants you the ability to ignore the most lethal of wounds. For 1d6 rounds you gain a +3 to all saving throws.

89) A rusty potion made of vinegar and metal dust that smells like chocolate and tastes of blood fills you with energy. For 1d12 rounds your Constitution is increased by 1d6 points.

90) A green potion made of moss and leaves that smells faintly of cedar and tastes like brandy allows you to ignore pain. For 1d12 rounds you gain a +6 to all saving throws against pain.

91) A smoky potion made of charcoal and ash that is cloudy and tastes of mint gives you the ability to regenerate. For 1d12 hours you gain 1 hp for every 4 rounds elapsed.

92) A black-brown potion made of liquid charcoal and coal that is jelly-like and tastes of mint allows you to see the hidden. For 1d12 rounds you can detect magical auras as if using detect magic.

93) A bubbly blue potion that is opaque and tastes faintly of cloves allows you to detect danger. For 1d12 hours you gain the ability to see auras as described under detect chaos/evil/good/law or detect undead if any such creatures are within 100 feet of you.

94) A blood-red potion the consistency of cream that tastes faintly of strawberries offers your mind protection from the powers of the Psi-wielders. For 1d12 rounds you gain resistance to psi-like effects (such as powers, spells, mind control, etc.) of all types except Psionic Blast.

95) A murky yellow potion that tastes faintly of cinnamon allows you to summon forth the powers of good. For 1d12 rounds any good powers cast within 50′ of you (whether a spell, psionic power, or other effect) are automatically absorbed and redeposited at a random location within 100 feet of you whether you wanted to or not. The original caster is not aware this is occurring if they have no psionics or powers themselves.

96) A black-brown potion that is thin and tastes faintly of honey allows you to attune yourself to the elemental plane which most embodies your own alignment (Chaotic, Evil, Good, Lawful). For 1d6 hours you gain resistance to fire and ice.

97) A creamy-white potion that smells like old flesh and tastes like honeyed brandy allows your body to become bloated with power. You gain +2 hp for every level of your character but suffer a -1 penalty to Dexterity for 1d12 hours.

98) A murky green potion that smells like fresh dirt and tastes like prune juice allows you to see into the future. For 1d12 rounds you gain a +1 insight bonus to Armor Class and all saving throws.

99) A cloudy lime-green potion that tastes of strawberries offers you the ability to speak with animals. For 1d12 hours you can understand any animal within 10′.

100) A rusty-brown potion with a texture like pudding and a taste of chicken feet will transform you into an ogre for 1d4 rounds. You gain +4 hp for every level of your character but suffer a -2 penalty to Dexterity.

Paul Bellow

LitRPG Author Paul Bellow

Paul Bellow is a LitRPG author, gamer, RPG game developer, and publisher of several online communities. In other words, an old school webmaster. He also developed and runs LitRPG Adventures, a set of advanced RPG generators powered by GPT-3 AI. Here at LitRPG Reads, he publishes articles about LitRPG books, tabletop RPG books, and all sorts of DND content that's free to use in your personal tabletop campaign - i.e. non-commercial use. Enjoy your stay and reach out on Twitter or Discord if you want to make contact.

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