100 D&D Random Drug Effects

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Here’s a list of 100 D&D random drug effects for your fantasy tabletop RPG. If you like what you see, head over to LitRPG Adventures to generate your own quality content. We’ve also got a library of thousands of already generated items, backstories, places, governments, and much more. Stop by today and give it a whirl. If you’re a DM, you’re going to find it very useful.

D&D Random Drug Effects

Feel free to change these as you see fit.

1) Goranza: This strange substance ia a foamy green liquid that smells like a cross between swamp water and a compost heap. It is a favorite among party animals and is particularly popular with fishermen, who will consume it before attempting to bring in the big one. Side effects include drowsiness, drenching sweats, and a general feeling of physical weakness.

2) Peycoyote: This tiny cactus is a common ingredient in potions of healing, but when chewed it has a different effect. The user will experience a powerful feeling of euphoria and will be inclined to laugh and giggle uncontrollably. It is a common ingredient in fertility potions.

3) Melange: A paste that is made from the flowers of the poppy and the petals from a variety of sunflowers. It is sold as a common drug but is extremely rare. It causes a state of total bliss and makes the user immensely drowsy.

4) Goblin Juice: A vile smelling, thick, sticky brown fluid that is made from the fermented sap of the Goblin’s favorite tree. The sap is collected by brave goblins, who climb the tree in the dead of night when the sap is most potent. They collect in clay pots and in a few days, when the sun is up and the sap has warmed, the pot will explode into a sticky, brown mess. If you drink this, you will have an out of body experience for several minutes. You will be able to feel the ground under your feet, but you will feel like you are being forced up.

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5) Horsefly Honey: In appearance, horsefly honey looks like a normal honey, but if you taste it, it tastes like the sweetest nectar you have ever tasted. However, if you eat too much, it will cause your skin to be covered in small red welts. Many bards use this to help them relax before a performance and it is especially good for helping with stage fright and nervousness.

6) Shind: This is a powder made from the dried and powdered bones of a large cat-like predator with the same name. If you consume too much, it will cause you to vomit and you will be incredibly weak. It is a common ingredient in tonics and potions that help to increase strength and stamina.

7) Dragon Sleep: A powder made from crushed dragon scales and the dust from smashed dragon eggs. When consumed, this slows down the heart beat and causes almost instant sleep. If enough is consumed, you will actually stop breathing and die. It is a favorite of assassins and is a key ingredient in a poison called the Black Lotus.

8) Sun Powder: This yellow powder is used to help keep pale skinned races tan and to keep dark skinned people from going very dark. It causes a slight uptick in your heart rate, which helps you to avoid sunburn.

9) Dragon Worms: These are the dried, ground up bodies of small worms that live under dragon scales. They are a common ingredient in healing potions and tonics.

10) Luck Dust: This golden powder is sprinkled on people before they make a big throw of the dice, drop something very valuable, or make any other big risky throw of the dice. It is made from the ground up bones of a recently deceased unlucky person.

11) Chameleon Moss: This is a moss that is known for its ability to change color to match its surroundings. When eaten, it causes the human body to change color to match the user’s surroundings. It is a favorite of thieves and assassins and is a very popular ingredient in invisibility potions.

12) Nix Mist: This is a yellowish green powder that causes you to feel slightly warm and causes a slight increase in heart rate. It makes you feel like the man or woman of the hour and causes you to feel like you can take on the world.

13) Gossamer: This is a powder made from the shell of the chrysalis of a moth. When ground up and put into a potion or tonic, it causes the user to feel like they are floating through the air.

14) Spider Silk: This is a thin, strong thread made from the silk of a giant spider. It helps to impart a sense of strength and helps to give you a greater sense of self confidence.

15) Blood Worms: Blood worms are small white worms that live in the earth. They have a very powerful healing spell and when ground up and put into tonics and potions, they cause a powerful healing effect.

16) Fly LSD: This is a fine powder that is the ground up wings of a large green fly. When taken, it causes a sense of mild intoxication and a great sense of euphoria.

17) Pixie Dust: This is a fine powder made from the crushed wings of pixies. It is a favorite of thieves and bards and is commonly used in invisibility potions.

18) Spider Silk: This is a thin, strong thread made from the silk of a giant spider. It helps to impart a sense of strength and helps to give you a greater sense of self confidence.

19) Egg Dust: The dried, powdered shells of eggs that are laid by the common crow. They are used to give you a greater sense of strength, stamina, and bravery.

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20) Black Lotus: This is a dark purple paste made from the juice of the Black Lotus flower. When spread on the skin, it causes large purple blotches. Some say it is made by demons or devils.

21) Unicorn Dust: This is a fine powder made from the dust of the hoof of a unicorn. When ingested it causes the user to become more empathetic and they will be more likely to do the right thing.

22) Bloodroot: This is the root of the Bloodroot plant. When ground up and ingested, your perception of time will be warped. One minute will seem like an hour.

23) Drow Dew: This is a fine powder made from the dust of crushed spider webs. It is used to counteract poison and disease. It causes the user to feel very relaxed and tranquil.

24) Bat Guano: The droppings of bats are used to make a fine powder. When put into tonics and potions, it helps to give you a sense of balance and poise.

25) Dragon Saliva: This is the magical substance that comes out of a dragon’s mouth. It is a bright, shining green liquid that will protect the user from all sorts of magical effects.

26) Basilisk Scales: The dried scales of the Basilisk are known to give the user some degree of protection against magic. When ground up and ingested, they make the user feel like they are protected by all forms of magic.

27) Minotaur Horn: The horns of a minotaur are ground up and put into potions and tonics to give the user a feeling of invulnerability.

28) Troll Feces: This is dried troll excrement that is ground up and put into potions and tonics. It is said to give the user some degree of protection against magic.

29) Hades Dust: This is a fine powder made from the petals of the Amaranth flower. When ingested, it gives the user a greater sense of clarity and focus. It also imparts a sense of peace and tranquility.

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30) Diamond Dust: This is the dust of ground up diamonds. When ingested it gives you a greater sense of clarity and focus.

31) Basilisk Scales: The dried scales of the Basilisk are known to give the user some degree of protection against magic. When ground up and ingested, they make the user feel like they are protected by all forms of magic.

32) Dragon Saliva: This is the magical substance that comes out of a dragon’s mouth. It is a bright, shining green liquid that will protect the user from all sorts of magical effects.

33) Dark Night: This root, when eaten, will cause the player to see in the dark.

34) Morning Dew: This is a magical liquid distilled from the morning dew. It is mostly clear with a slight green tint. It is put into potions and tonics to provide health and healing benefits.

35) Sea Mist: Sea mist is a magical liquid distilled from the sea. When drank, it causes a person to hallucinate and think they are being attacked by a water elemental.

36) Red Root: The effects of this drug are well known. When eaten, it gives the user a sense of bravery and courage.

37) Black Root: This plant gives the user a feeling of sorrow and regret.

38) Green Root: This root makes the user feel determined and in control.

39) Yellow Root: This root makes the user feel like they are filled with tremendous energy.

40) Brown Root: This root makes the user feel like they are filled with an abundance of positive energy.

41) White Root: This root, when eaten, will cause the user to feel invisible to anyone or anything that might want to attack them.

42) Purple Root: This root, when eaten, will cause the user to become invisible to normal sight and even darkvision.

43) Red Leaf: This leaf has a somewhat bitter taste and gives the user a sense of courage and bravery.

44) Black Leaf: This leaf is extremely bitter, and gives the user a sense of sorrow and regret.

45) Green Leaf: This leaf is not bitter and gives the user a sense of determination and control.

46) Yellow Leaf: This leaf is bitter and gives the user a sense of being filled with energy.

47) Brown Leaf: This leaf is not bitter and gives the user a sense of being filled with a positive amount of energy.

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48) White Leaf: This leaf is not bitter and gives the user a sense of being filled with an abundance of positive energy.

49) Purple Leaf: This leaf is not bitter, and gives the user a sense of invisibility.

50) Rose Petals: This plant is known for giving the user a sense of peacefulness.

51) Lavender Petals: This plant is known for making the user feel like they are protected against all forms of magic.

52) Lilac Petals: This plant is known for making the user feel like they are protected against all forms of physical attacks.

53) Red Petals: This plant is known for making the user feel like they are protected against all forms of fire. They are not actually protected.

54) Black Petals: This plant is known for making the user feel cold.

55) Green Petals: This plant is known for making the user feel like they are protected against all forms of poison.

56) Yellow Petals: When ingested with water, the effects of this drug are known to give the user a sense of invulnerability.

57) Brown Petals: When ingested with water, the effects of this drug cause the user to hallucinate and think they are being attacked by a fire elemental.

58) White Petals: When ingested with water, the effects of this drug cause the user to hallucinate and think they are being attacked by a water elemental.

59) Purple Petals: When ingested with water, the effects of this drug cause the visual senses of the user to become distorted and warped.

60) Red Powder: This is a very fine, red powder that is made from the petals of the rose. When ingested, it gives the user a sense of invulnerability and a feeling like they are protected from all forms of physical and magical attack. This, however, is not the case. They will be more susceptible to damage.

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61) Sunset Horror: This strange drug is known to cause the user to hallucinate and become aggressive towards themselves and those around them.

62) Sly Serpent: When this drug is ingested, the user is known to become very sneaky and manipulative.

63) Blue Powder: This is a fine blue powder made from the petals of the blue rose. When ingested, it causes the user to feel like they’re special.

64) Lightning Flower: When this drug is ingested, the effects will make the user feel like their mind is racing.

65) Purple Powder: This is a fine purple powder made from the petals of the purple rose. When ingested, it is known to cause the user to become desirous of sex.

66) Wolfbane: When this drug is ingested, the user will become lethargic, almost as if they were dead, but will be able to see and hear everything around them.

67) Green Powder: This is a fine, green powder made from the petals of the green rose. When ingested, it is known to cause the user to have uncontrollable movements causing them to dance uncontrollably.

68) White Powder: This is a fine, white powder made from the petals of the white rose. When ingested, it is known to cause the user to feel like they are being watched by some malevolent entity.

69) Lesser Mindstone: This is a small, green crystal. When ingested, it is known to heighten the users mental capabilities and give them a greater grasp on the magical arts.

70) Mindstone: This is a small, blue crystal. When ingested, it is known to heighten the users mental capabilities and give them a greater grasp on the magical arts.

71) Greater Mindstone: This is a small, red crystal. When ingested, it is known to heighten the users mental capabilities and give them a greater grasp on the magical arts.

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72) Confusion Dust: This is a fine, brown dust. When eaten, it is known to cause the user to become confused and possibly comatose.

73) Blue Powder: This is a fine blue powder. When taken, it is known to cause the user to hallucinate and think they are walking on water.

74) Red Powder: This is a fine, red powder. The effects of this drug will make the user feel like they are breathing fire.

75) Green Dust: This is a fine, green dust. When taken, it is known to cause the user to hallucinate and think they are breathing grass.

76) Purple Powder: When this drug is ingested, the player will feel as if they have been poisoned, suffering from a headache and possibly paralysis.

77) Sleeping Powder: When this drug is ingested, the user will begin to feel drowsy and may fall asleep.

78) Blue Dust: When this drug is ingested, the user will begin to feel as if they have been poisoned, suffering from a headache and possibly paralysis.

79) Yellow Powder: This is a fine, yellow powder. When ingested, it is known to cause the user to hallucinate and think they are walking on fire.

80) Gold Dust: This is a fine, gold dust. When ingested, it is known to cause the user to hallucinate and think they are walking on water.

81) Pink Powder: When this drug is ingested, the user will become desirous of sex and want to mate with another.

82) Purple Dust: The effects of this drug will make the user think they are surrounded by a field of flowers.

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83) Silver Dust: The effects of this drug will make the user think they are surrounded by a field of grass.

84) Vacuity Dust: This is a fine, black dust. When ingested, it is known to cause the user to be struck by a feeling of overwhelming emptiness.

85) Blue Dust: This is a fine, blue dust. When this drug is ingested, the user will feel as if they have been poisoned, suffering from a headache and possibly paralysis.

86) Black Powder: When this drug is ingested, the user will begin to feel drowsy and may fall asleep.

87) Mind Dust: When this drug is ingested, the user will begin to feel as if they have been poisoned, suffering from a headache.

88) Gold Dust: When eaten in copious amounts, this drug will cause the user to be struck by a feeling of euphoria, but will cause the user to become extremely lethargic and possibly comatose.

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89) Minddust: This is a fine, green dust. When ingested, it is known to cause the user to be struck by a feeling of overwhelming emptiness.

90) Gomtun Root: This dangerous drug’s effects include: 1) hallucinations, 2) obsession with material goods, and 3) paranoia.

91) Yellow Dust: This is a fine, yellow dust. When ingested, the user will become desirous of sex and want to mate with anyone they see.

92) Indigo Dust: This is a fine, indigo dust. When ingested, its effects are quick and lethal. The drug will cause a person to die a peaceful death.

93) Green Durten: A strange drug, Green Durten’s effects are known to include: 1) a sense of wellbeing, 2) a desire for sex, and 3) a tendency to talk in rhymes.

94) Goshen: When this drug is taken orally, the user will tell the truth no matter what.

95) Tworang: The effects of this drug are harsh. The user will become extremely violent and hostile toward everyone, including friends and loved ones.

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96) Slumber Dust: When ingested, this fine, white dust will cause the user to fall into a deep sleep.

97) Nightcrawler: When this drug is taken orally, the user will fall into a deep sleep, but will have nightmarish dreams of their own death.

98) Camsyd Redd: Camsyd Redd is a drug that is snorted. When ingested, its effects are powerful, but not long-lasting. When the user comes down from Camsyd Redd, they will be extremely tired, but will be able to fall asleep almost instantly.

99) Yellow Dew: This powder is yellow in color. When snorted, it is known to cause hallucinations.

100) Cerulean Dust: This is a fine, cerulean dust. When taken orally, the user will have their face permanently stained with a cerulean-purple hue.

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